diff --git a/extensions/vtk/src/commandsModule.js b/extensions/vtk/src/commandsModule.js
index 901b2a853..dcd1e2d7e 100644
--- a/extensions/vtk/src/commandsModule.js
+++ b/extensions/vtk/src/commandsModule.js
@@ -17,6 +17,7 @@ const { BlendMode } = Constants;
 const commandsModule = ({ commandsManager, UINotificationService }) => {
   // TODO: Put this somewhere else
   let apis = {};
+  let defaultVOI;
 
   async function _getActiveViewportVTKApi(viewports) {
     const {
@@ -119,9 +120,11 @@ const commandsModule = ({ commandsManager, UINotificationService }) => {
       return apis[index];
     },
     resetMPRView() {
-      apis.forEach(api => {
-        api.resetOrientation();
-      });
+      // Reset orientation
+      apis.forEach(api => api.resetOrientation());
+
+      // Reset VOI
+      if (defaultVOI) setVOI(defaultVOI);
 
       // Reset the crosshairs
       apis[0].svgWidgets.rotatableCrosshairsWidget.resetCrosshairs(apis, 0);
@@ -172,7 +175,7 @@ const commandsModule = ({ commandsManager, UINotificationService }) => {
       segmentNumber,
       frameIndex,
       frame,
-      done = () => {},
+      done = () => { },
     }) => {
       let api = apis[viewports.activeViewportIndex];
 
@@ -387,6 +390,7 @@ const commandsModule = ({ commandsManager, UINotificationService }) => {
 
       // Get current VOI if cornerstone viewport.
       const cornerstoneVOI = getVOIFromCornerstoneViewport();
+      defaultVOI = cornerstoneVOI;
 
       const viewportProps = [
         {