diff --git a/extensions/cornerstone/src/initMeasurementService.ts b/extensions/cornerstone/src/initMeasurementService.ts
index d66ef291b..93eabddd5 100644
--- a/extensions/cornerstone/src/initMeasurementService.ts
+++ b/extensions/cornerstone/src/initMeasurementService.ts
@@ -503,11 +503,15 @@ const connectMeasurementServiceToTools = ({
       }
       const removedAnnotation = annotation.state.getAnnotation(removedMeasurementId);
       removeAnnotation(removedMeasurementId);
-      commandsManager.run('triggerCreateAnnotationMemo', {
-        annotation: removedAnnotation,
-        FrameOfReferenceUID: removedAnnotation.metadata.FrameOfReferenceUID,
-        options: { deleting: true },
-      });
+      // Ensure `removedAnnotation` is available before triggering the memo,
+      // as it can be undefined during an undo operation
+      if (removedAnnotation) {
+        commandsManager.run('triggerCreateAnnotationMemo', {
+          annotation: removedAnnotation,
+          FrameOfReferenceUID: removedAnnotation.metadata.FrameOfReferenceUID,
+          options: { deleting: true },
+        });
+      }
       const renderingEngine = cornerstoneViewportService.getRenderingEngine();
       // Note: We could do a better job by triggering the render on the
       // viewport itself, but the removeAnnotation does not include that info...