diff --git a/extensions/tmtv/src/Panels/PanelROIThresholdSegmentation/PanelROIThresholdSegmentation.tsx b/extensions/tmtv/src/Panels/PanelROIThresholdSegmentation/PanelROIThresholdSegmentation.tsx
index 1b946c6cf..998eb24bb 100644
--- a/extensions/tmtv/src/Panels/PanelROIThresholdSegmentation/PanelROIThresholdSegmentation.tsx
+++ b/extensions/tmtv/src/Panels/PanelROIThresholdSegmentation/PanelROIThresholdSegmentation.tsx
@@ -9,10 +9,10 @@ import ROIThresholdConfiguration, {
   ROI_STAT,
 } from './ROIThresholdConfiguration';
 
-const LOWER_CT_THRESHOLD_DEFAULT = -1000;
-const UPPER_CT_THRESHOLD_DEFAULT = 500;
-const LOWER_PT_THRESHOLD_DEFAULT = 5;
-const UPPER_PT_THRESHOLD_DEFAULT = 50;
+const LOWER_CT_THRESHOLD_DEFAULT = -1024;
+const UPPER_CT_THRESHOLD_DEFAULT = 1024;
+const LOWER_PT_THRESHOLD_DEFAULT = 2.5;
+const UPPER_PT_THRESHOLD_DEFAULT = 100;
 const WEIGHT_DEFAULT = 0.41; // a default weight for suv max often used in the literature
 const DEFAULT_STRATEGY = ROI_STAT;
 
diff --git a/extensions/tmtv/src/utils/getThresholdValue.ts b/extensions/tmtv/src/utils/getThresholdValue.ts
index a54171f6a..d11872dd0 100644
--- a/extensions/tmtv/src/utils/getThresholdValue.ts
+++ b/extensions/tmtv/src/utils/getThresholdValue.ts
@@ -50,10 +50,9 @@ function getThresholdValues(
   );
 
   const ptValue = getRoiStats(referencedVolumes[0], annotations);
-  const ctValue = getRoiStats(referencedVolumes[1], annotations);
 
   return {
-    ctLower: weight * ctValue,
+    ctLower: -Infinity,
     ctUpper: +Infinity,
     ptLower: weight * ptValue,
     ptUpper: +Infinity,