diff --git a/extensions/default/src/DicomJSONDataSource/index.js b/extensions/default/src/DicomJSONDataSource/index.js
index deb50e252..bf21a77e8 100644
--- a/extensions/default/src/DicomJSONDataSource/index.js
+++ b/extensions/default/src/DicomJSONDataSource/index.js
@@ -169,7 +169,7 @@ function createDicomJSONApi(dicomJsonConfig) {
         return getDirectURL(dicomJsonConfig, params);
       },
       series: {
-        metadata: async ({ StudyInstanceUID, madeInClient = false, customSort } = {}) => {
+        metadata: async ({ filters, StudyInstanceUID, madeInClient = false, customSort } = {}) => {
           if (!StudyInstanceUID) {
             throw new Error('Unable to query for SeriesMetadata without StudyInstanceUID');
           }
@@ -183,6 +183,18 @@ function createDicomJSONApi(dicomJsonConfig) {
             series = study.series;
           }
 
+          const seriesKeys = [
+            'SeriesInstanceUID',
+            'SeriesInstanceUIDs',
+            'seriesInstanceUID',
+            'seriesInstanceUIDs',
+          ];
+          const seriesFilter = seriesKeys.find(key => filters[key]);
+          if (seriesFilter) {
+            const seriesUIDs = filters[seriesFilter];
+            series = series.filter(s => seriesUIDs.includes(s.SeriesInstanceUID));
+          }
+
           const seriesSummaryMetadata = series.map(series => {
             const seriesSummary = {
               StudyInstanceUID: study.StudyInstanceUID,
diff --git a/platform/app/src/routes/Mode/Mode.tsx b/platform/app/src/routes/Mode/Mode.tsx
index 0e78c74be..783356dda 100644
--- a/platform/app/src/routes/Mode/Mode.tsx
+++ b/platform/app/src/routes/Mode/Mode.tsx
@@ -239,18 +239,15 @@ export default function ModeRoute({
       const filters =
         Array.from(query.keys()).reduce((acc: Record<string, string>, val: string) => {
           const lowerVal = val.toLowerCase();
-          if (lowerVal !== 'studyinstanceuids') {
-            // Not sure why the case matters here - it doesn't in the URL
-            if (lowerVal === 'seriesinstanceuids') {
-              const seriesUIDs = getSplitParam(lowerVal, query);
-              return {
-                ...acc,
-                seriesInstanceUID: seriesUIDs,
-              };
-            }
-
-            return { ...acc, [val]: getSplitParam(lowerVal, query) };
+          // Not sure why the case matters here - it doesn't in the URL
+          if (lowerVal === 'seriesinstanceuids') {
+            const seriesUIDs = getSplitParam(lowerVal, query);
+            return {
+              ...acc,
+              seriesInstanceUID: seriesUIDs,
+            };
           }
+          return { ...acc, [val]: getSplitParam(lowerVal, query) };
         }, {}) ?? {};
 
       let unsubs;