diff --git a/Packages/ohif-servers/both/schema/servers.js b/Packages/ohif-servers/both/schema/servers.js
index 5a0a224e0..93e87d3e2 100644
--- a/Packages/ohif-servers/both/schema/servers.js
+++ b/Packages/ohif-servers/both/schema/servers.js
@@ -180,6 +180,11 @@ export const UISettings = new SimpleSchema({
         type: Boolean,
         label: 'Define if the series\' images shall be sorted by incoming order. Sort by Instance Number by default.',
         defaultValue: false
+    },
+    useMiddleSeriesInstanceAsThumbnail: {
+        type: Boolean,
+        label: 'Define if the middle instance of a series will be used as thumbnail. If not, the first instance will be used.',
+        defaultValue: true
     }
 });
 
diff --git a/Packages/ohif-viewerbase/client/components/studyBrowser/imageThumbnail/imageThumbnail.js b/Packages/ohif-viewerbase/client/components/studyBrowser/imageThumbnail/imageThumbnail.js
index bf658f017..d59c1c38a 100644
--- a/Packages/ohif-viewerbase/client/components/studyBrowser/imageThumbnail/imageThumbnail.js
+++ b/Packages/ohif-viewerbase/client/components/studyBrowser/imageThumbnail/imageThumbnail.js
@@ -1,3 +1,4 @@
+import { Meteor } from 'meteor/meteor';
 import { Template } from 'meteor/templating';
 import { Tracker } from 'meteor/tracker';
 import { Session } from 'meteor/session';
@@ -8,16 +9,18 @@ Template.imageThumbnail.onCreated(() => {
 
     // Get the image ID for current thumbnail
     instance.getThumbnailImageId = () => {
+        const settingPath = 'public.ui.useMiddleSeriesInstanceAsThumbnail';
+        const useMiddleFrame = OHIF.utils.ObjectPath.get(Meteor.settings, settingPath);
         const stack = instance.data.thumbnail.stack;
         const lastIndex = (stack.numImageFrames || stack.images.length || 1) - 1;
-        let imageIndex = Math.floor(lastIndex / 2);
+        let imageIndex = useMiddleFrame ? Math.floor(lastIndex / 2) : 0;
         let imageInstance;
 
         if (stack.isMultiFrame) {
             imageInstance = stack.images[0];
         } else {
             imageInstance = stack.images[imageIndex];
-            imageIndex = 0;
+            imageIndex = undefined;
         }
 
         return imageInstance.getImageId(imageIndex, true);